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Cell Size

Unit 2 · Topic 2.2 end-of-topic test

Answer every question. For each multiple-choice question, pick one option and press Check; the feedback tells you what a wrong choice assumed. For the two free-response questions, write your answer in full sentences, then open the scoring guide and mark your own work against it. Formulas are given wherever a calculation needs them; use π = 3.14.
Question 1

A model cell is a cube with sides of 3 μm. For a cube of side s, surface area = 6s² and volume = s³.

What are its surface area and its volume?

Question 2

A cube-shaped cell has a surface area of 150 μm² and a volume of 125 μm³.

What is its surface-area-to-volume ratio?

Question 3

For the 2 μm cube (surface area 24 μm², volume 8 μm³), a student writes: SA/V = 8 ÷ 24 = 0.33 μm.

What is wrong with the student's working?

Question 4

A yeast cell grows before it divides. Its diameter increases from 4 μm to 8 μm while its shape stays the same.

Compared with the smaller cell, how have its surface area, volume and surface-area-to-volume ratio changed?

Question 5

Four cube-shaped model cells: Model K has a surface area of 150 μm² and a volume of 125 μm³; Model L, 54 μm² and 27 μm³; Model M, 24 μm² and 8 μm³; Model N, 96 μm² and 64 μm³.

Which model would exchange materials with its surroundings most efficiently, and why?

Question 6

Cells in a plant tissue are modeled as cubes. A 10 μm cube's membrane can bring in at most 120 units of oxygen a minute, and the cell uses 100 units a minute. Oxygen intake is proportional to membrane area; oxygen use is proportional to volume.

What percentage of its oxygen need can the membrane supply in a 20 μm cube and in a 30 μm cube?

Question 7

A student writes: "A larger cell exchanges materials with its surroundings more efficiently than a smaller one, because it has more membrane."

Which statement about the larger cell corrects the student?

Question 8

Two samples of cells from the lining of the small intestine are compared. The cells in one sample have microvilli, folds of the plasma membrane, and have three times the membrane area of the cells in the other sample. Both kinds of cell have the same volume. Under the same conditions, the cells with microvilli take up nutrients 2.7 times as fast.

Why do the cells with microvilli take up nutrients faster?

Question 9

On the underside of a leaf are thousands of tiny pores, each set between a pair of cells. When the pores are open, air reaches the many cell surfaces inside the leaf; when they are shut, the air stays outside.

What are the pores and the paired cells, and how do the cells open the pore?

Question 10

Root cells of the same plant each grow a single thin outgrowth into the soil. Cells whose outgrowths are 0.2 mm, 0.6 mm and 1.0 mm long take up water at 0.8, 1.9 and 3.1 units a minute. The outgrowths are all about the same width.

What is the outgrowth, and why does a longer one take up water faster?

Question 11

A mouse weighs about 20 g; an elephant weighs about 4,000 kg. Both keep their bodies at about 37 °C in cool air.

Which animal loses more heat each hour in total, and which loses more heat each hour per gram of body?

Question 12

Three mammals rest in the same cool room. A shrew (mass 5 g) loses 30 units of heat per gram per hour; a rabbit (2,000 g) loses 4 units per gram per hour; a cow (500,000 g) loses 0.5 units per gram per hour.

What explains this pattern?

Question 13

A mouse eats about a fifth of its body mass in food every day. An elephant eats about 4% of its body mass a day. The food an animal eats each day supplies the energy it uses.

What does this show about the metabolic rates of the two animals?

Question 14

A spherical cell has a radius of 3 μm. For a sphere, surface area = 4πr² and volume = 4/3 πr³. Use π = 3.14.

What are its surface area, volume and surface-area-to-volume ratio?

Question 15

A flattened cell is modeled as a rectangular solid 10 μm long, 5 μm wide and 0.5 μm thick. For a rectangular solid, surface area = 2lh + 2lw + 2wh and volume = lwh.

What are its surface area, volume and surface-area-to-volume ratio?

Question 16

Two cells are compared: a spherical cell 5 μm across (radius 2.5 μm) and a cube-shaped cell with sides of 7 μm. Sphere: surface area = 4πr², volume = 4/3 πr³; cube: 6s² and s³. Use π = 3.14.

Which cell exchanges materials with its surroundings more efficiently, and why?

Question 17

Two blood cells each have a volume of 90 μm³. One is flattened and has 120 μm² of plasma membrane; the other is nearly spherical and has 100 μm² of plasma membrane.

Which cell exchanges materials more efficiently, and what does that say about its shape?

How to tackle the free-response questions. Read the verb first: describe asks what you see or know; explain asks why or how, so name the mechanism; predict asks what will happen and why; justify asks for the evidence that supports a claim. Each point is earned by one idea, stated in a sentence that names the thing and the mechanism. Extra words earn nothing; a wrong extra can lose the point. If there is a figure or table, use what it shows. When you finish, check the box for each point your answer earns and compare your sentences with the full-credit answer.
Free response 1 · Analyze Model or Visual Representation · 4 points
The model shows three cube-shaped cells with sides of 2 μm, 4 μm and 8 μm. For a cube of side s, surface area = 6s² and volume = s³. The 2 μm cell has a surface area of 24 μm², a volume of 8 μm³ and a surface-area-to-volume ratio of 3 per μm. The 4 μm cell has 96 μm², 64 μm³ and 1.5 per μm. The values for the 8 μm cell are left blank. Everything a cell takes in, and every waste it gets rid of, crosses its surface.
side 2 μmside 4 μmside 8 μm24 μm², 8 μm³96 μm², 64 μm³? μm², ? μm³
Three cube-shaped model cells drawn to the same scale, with the surface area and volume of the first two.

(a) Describe how the surface area and the volume change each time the side of the cell doubles, using the numbers for the 2 μm and 4 μm cells. (1 point)

A full-credit answer: When the side doubles from 2 to 4 μm, the surface area is multiplied by 4, from 24 to 96 μm², while the volume is multiplied by 8, from 8 to 64 μm³. The volume grows faster than the surface area, so the surface-area-to-volume ratio halves, from 3 to 1.5 per μm.

Write down the values in the question:

2 μm cell: surface area = 24 μm², volume = 8 μm³
4 μm cell: surface area = 96 μm², volume = 64 μm³

Write down the equation:

          value for the 4 μm cell
factor = ─────────────────────────
          value for the 2 μm cell

Substitute in the values, and calculate:

surface area factor = 96 ÷ 24
surface area factor = 4
volume factor = 64 ÷ 8
volume factor = 8

Check the box for each point your answer earns

Accept: "surface ×4, volume ×8" with the numbers from the model cited. Do not award the point for "both get bigger" or "the volume gets bigger" with no factors or numbers.

Common slip: Saying both get bigger. The point needs the factors, 4 for surface and 8 for volume, or the ratio halving.

(b) Explain why a falling surface-area-to-volume ratio limits how large a cell can grow. (1 point)

A full-credit answer: A cell takes in what it needs and gets rid of wastes only across its surface, while the amount it needs and the waste it makes grow with its volume. As the cell grows its surface cannot keep up with its interior, so past a certain size the surface cannot supply the volume.

Check the box for each point your answer earns

Accept: "there is not enough membrane to supply the volume" or "exchange across the surface cannot keep pace with the demand of the interior". Do not award the point for "the cell gets too big" with no reference to both surface and volume.

Common slip: Saying the cell gets too big. The point needs both halves: exchange happens across the surface, and need grows with the volume.

(c) Complete the model for the 8 μm cell: give its surface area, its volume and its surface-area-to-volume ratio, each with its unit. (1 point)

A full-credit answer: The 8 μm cell has a surface area of 384 μm², a volume of 512 μm³ and a surface-area-to-volume ratio of 0.75 per μm.

Write down the values in the question:

s = 8 μm

Write down the equations:

surface area = 6s²
volume = s³
        surface area
SA/V = ──────────────
           volume

Substitute in the values, and calculate:

surface area = 6 × 8²
surface area = 6 × 64
surface area = 384 μm²
volume = 8³
volume = 512 μm³
SA/V = 384 ÷ 512
SA/V = 0.75 per μm

Check the box for each point your answer earns

Accept: 0.75 μm⁻¹ or "3 : 4" for the ratio. Do not award the point if the ratio is inverted (1.33) or if the units are missing from all three values.

Common slip: Inverting the ratio to 1.33, or leaving the units off. The ratio is surface area divided by volume, in per μm.

(d) Explain how the pattern in the model relates to the way living cells are built: either to the fact that cells stay small or divide, or to the folded membranes of cells specialized for exchange, such as the microvilli on the cells lining the gut. (1 point)

A full-credit answer: Because the ratio falls as a cell grows, a cell stays small or divides rather than growing without limit, so its surface keeps up with the interior it has to supply. A cell built for exchange goes further: folding its membrane into microvilli adds surface while adding almost no volume, raising the ratio so that exchange keeps pace with the interior.

Check the box for each point your answer earns

Accept: either link made in full (the pattern in the model tied to the reason). Do not award the point for naming microvilli or division without saying what they do to surface relative to volume.

Common slip: Naming microvilli or division without saying what they do to surface relative to volume. Tie the structure to the ratio.

Free-response score: 0 of 4
Free response 2 · Conceptual Analysis · 4 points
In pond water live a single-celled alga, modeled as a sphere of radius 2 μm, and a rod-shaped bacterium, modeled as a cylinder of radius 0.5 μm and length 4 μm. Both take up dissolved nutrients across their surfaces. Formulas: sphere, surface area = 4πr², volume = 4/3 πr³; cylinder, surface area = 2πrh + 2πr², volume = πr²h. Use π = 3.14.

(a) Calculate the surface-area-to-volume ratio of each cell, showing the surface area and the volume you used, with units. (1 point)

A full-credit answer: The alga’s surface-area-to-volume ratio is 1.5 per μm, from 50.2 μm² of surface and 33.5 μm³ of volume. The bacterium’s is 4.5 per μm, from 14.1 μm² and 3.14 μm³.

Write down the values in the question:

alga: r = 2 μm, π = 3.14
bacterium: r = 0.5 μm, h = 4 μm, π = 3.14

Write down the equations:

sphere: surface area = 4πr², volume = (4/3)πr³
cylinder: surface area = 2πrh + 2πr², volume = πr²h
        surface area
SA/V = ──────────────
           volume

Substitute in the values, and calculate:

alga surface area = 4 × 3.14 × 2²
alga surface area = 50.2 μm²
alga volume = (4/3) × 3.14 × 2³
alga volume = 33.5 μm³
alga SA/V = 50.2 ÷ 33.5
alga SA/V = 1.5 per μm
bacterium surface area = 2 × 3.14 × 0.5 × 4 + 2 × 3.14 × 0.5²
bacterium surface area = 12.56 + 1.57
bacterium surface area = 14.1 μm²
bacterium volume = 3.14 × 0.5² × 4
bacterium volume = 3.14 μm³
bacterium SA/V = 14.1 ÷ 3.14
bacterium SA/V = 4.5 per μm

Check the box for each point your answer earns

Accept: ratios given with the working shown, even if one intermediate value is rounded differently. Do not award the point for inverted ratios (volume ÷ surface) or for one cell only.

Common slip: Dividing volume by surface area, or working out one cell only. Surface over volume, for both cells.

(b) Identify which cell exchanges nutrients with the water more efficiently, for its size, and explain why. (1 point)

A full-credit answer: The bacterium. It has three times as much surface for each unit of volume, 4.5 against 1.5 per μm, and everything a cell takes in crosses its surface while what it needs grows with its volume, so each μm³ of the bacterium is supplied across more membrane.

Check the box for each point your answer earns

Accept: "the bacterium; a higher surface-area-to-volume ratio means more membrane per unit of interior to exchange across". Do not award the point for "the bacterium because it is smaller" with no link to surface per unit of volume.

Common slip: Saying the bacterium because it is smaller, with no link to surface per unit of volume. Small helps only because it raises the ratio.

(c) Predict what happens to the alga's surface-area-to-volume ratio, and to how well its surface can supply its interior, if it grows to a radius of 4 μm before dividing. (1 point)

A full-credit answer: Doubling the radius multiplies the surface by 4, to about 201 μm², and the volume by 8, to about 268 μm³, so the ratio halves to 0.75 per μm. The surface supplies the interior less well: exchange cannot keep pace with the larger volume.

Write down the values in the question:

r = 4 μm
π = 3.14

Write down the equations:

surface area = 4πr²
volume = (4/3)πr³
        surface area
SA/V = ──────────────
           volume

Substitute in the values, and calculate:

surface area = 4 × 3.14 × 4²
surface area = 201 μm²
volume = (4/3) × 3.14 × 4³
volume = 268 μm³
SA/V = 201 ÷ 268
SA/V = 0.75 per μm

Check the box for each point your answer earns

Accept: "the ratio falls (halves) and exchange becomes less efficient" with the direction of both changes stated. Do not award the point for "the ratio rises because the cell has more surface".

Common slip: Saying the ratio rises because the cell has more surface. It has more surface in total but far more volume, so less surface for each μm³.

(d) A related alga has the same volume as the 2 μm-radius sphere (33.5 μm³) but grows as a flat disk 0.5 μm thick, with about 150 μm² of surface. Justify the claim that this flat shape is an aid to exchange. (1 point)

A full-credit answer: At the same volume, 33.5 μm³, the disk has about three times the surface, 150 μm² against 50.2 μm², so its ratio is about 4.5 per μm against 1.5. More surface per unit of volume means nutrients can be exchanged faster for the same interior, so the flat shape aids exchange.

Write down the values in the question:

surface area = 150 μm²
volume = 33.5 μm³

Write down the equation:

        surface area
SA/V = ──────────────
           volume

Substitute in the values, and calculate:

SA/V = 150 ÷ 33.5
SA/V = 4.5 per μm

Check the box for each point your answer earns

Accept: the comparison stated as "more surface for the same volume, so a higher ratio and faster exchange" without the 4.5 figure. Do not award the point for "flat cells are smaller" or for a claim with no comparison of surface to volume.

Common slip: Saying flat cells are smaller. The volume is the same; the shape adds surface, and that is what raises the ratio.

Free-response score: 0 of 4
Multiple choice checked: 0 of 17 correct.