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Practice questions · Topic 5.2

Unit 5 · Practice for the Topic 5.2 end-of-topic test

You’ve gone through everything in this topic. The summary video below recaps it all, so you’re ready for the questions.

Watch first: Meiosis and genetic diversity, summed up

Video coming soon

Pairs that line up on their own and the two to the power of the pairs; non-sister chromatids trading pieces; any egg with any sperm; when a pair fails to separate, and how the counts say which division failed.

These are practice questions in the shape of the topic test. Work through them before you take the test; every question tells you what it wanted.
Answer every question. For each multiple-choice question, pick one option and press Check; the feedback gives the reasoning. For the free-response questions, write one short sentence for each step of your reasoning, each on its own line, and make every link clear (so, because, therefore). That is what the exam’s ‘paragraph form’ means for you: linked sentences, not bullet points. Show any calculation. The first free-response question walks you through one nondisjunction one part at a time, and you can open a hint for each part; the second is at the level of the test. When you finish a question, open the scoring guide and mark your own work against it.
Question 1

A gamete from a dragonfly carries one chromosome of every pair.

Which statement describes where the chromosomes in that gamete came from?

Question 2

An animal’s body cells hold 10 pairs of chromosomes.

How many kinds of gamete can one of these animals make by independent orientation alone?

Question 3

In prophase I in a bee, two chromatids break at the same point and exchange pieces.

Which two chromatids are they?

Question 4

In a squirrel, the maternal homolog of a pair carries R at one position and T at the next position along the same arm; the paternal homolog carries r and t. After one crossover between the two positions, the four chromatids read R with T, R with t, r with T and r with t.

Which two are the parental combinations?

Question 5

In a species of animal, each parent makes 16 kinds of gamete by independent orientation.

How many kinds of zygote can two of these animals make, counting independent orientation and random fertilization only?

Question 6

One chromatid in a guinea pig’s egg carries the mother’s allele of one gene and the father’s allele of the next gene along the same chromosome.

In which stage of meiosis did that chromatid form?

Question 7

An animal’s body cells hold 30 chromosomes. In one cell, one homologous pair undergoes nondisjunction in meiosis I; meiosis II is normal.

What are the chromosome counts of the four cells produced?

Question 8

An insect’s body cells hold 14 chromosomes. The four cells from one meiosis hold 8, 6, 7 and 7.

Which division did the failure happen in?

Question 9

A sheep’s body cells hold 54 chromosomes. A sheep egg with 28 chromosomes is fertilized by a normal sperm with 27.

What does the zygote hold?

Question 10

One parent of a species of animal makes 2,048 kinds of gamete by independent orientation alone.

How many pairs of chromosomes does this animal have?

How to tackle the free-response questions. Read the verb first: describe asks what you see or know; explain asks why or how, so name the mechanism; predict asks what will happen and why; justify asks for the evidence that supports a claim. Each point is earned by one idea, stated in a sentence that names the thing and the mechanism. Extra words earn nothing; a wrong extra can lose the point. If there is a figure or table, use what it shows. When you finish, check the box for each point your answer earns and compare your sentences with the full-credit answer.
Free response 1 · Conceptual Analysis · 5 points
A plant’s body cells each hold 8 chromosomes. One cell in its anther, the part of the flower that makes pollen, goes through meiosis.

(a) Calculate the number of chromosomes in each of the four cells when meiosis is normal. (1 point)

Hint: How many pairs does a cell with 8 chromosomes have, and how many of each pair does a gamete get?

Write down the values in the question:

2n=8

Write down the equation:

chromosomes per gamete=n=2n2

Substitute the values into the equation:

chromosomes per gamete=82=4

A full-credit answer: Each of the four cells holds 4 chromosomes, one of every pair.

(b) Predict the four counts if one homologous pair undergoes nondisjunction in meiosis I and meiosis II is normal. (1 point)

Hint: In meiosis I both members of one pair go to one cell; what does meiosis II then do to each of the two cells?

A full-credit answer: The cell that receives both members holds 5, the other holds 3, and meiosis II copies each into two cells: 5, 5, 3, 3.

Check the box for each point your answer earns

Common slip: Writing 5, 3, 4, 4. That is the pattern of a failure in meiosis II.

(c) Predict the four counts if instead meiosis I is normal and, in one of the two cells, the sister chromatids of one chromosome undergo nondisjunction in meiosis II. (1 point)

Hint: Only one of the two cells from meiosis I fails; what does the other cell give?

A full-credit answer: The cell that failed gives 5 and 3; the other cell gives 4 and 4, the normal count.

Check the box for each point your answer earns

Common slip: Writing 5, 5, 3, 3. Only one cell failed, so two of the four are normal.

(d) A set of four cells from a second plant, whose body cells hold 34 chromosomes, holds 18, 18, 16 and 16. Determine the division in which the failure happened, using the counts. (1 point)

Hint: Compare this set with the two patterns you predicted in (b) and (c).

A full-credit answer: The normal count for this plant is 17.
None of the four cells holds 17, so all four are abnormal.
Only a failure in meiosis I makes both cells it produces abnormal.
So the failure was in meiosis I.
Meiosis II then copied each count into two cells: 18, 18, 16 and 16.

Check the box for each point your answer earns

Common slip: Choosing meiosis II because a cell is over and a cell is under. Both patterns have that; the cells with the normal count place the failure.

(e) Return to the first plant, with 8 chromosomes. Predict the chromosome number of the zygote made when one of the gametes with the extra chromosome from part (b) fuses with a normal gamete, and identify it as a trisomy or a monosomy. (1 point)

Hint: Add the abnormal gamete’s count to a normal gamete’s count, then ask how many copies of the extra chromosome the zygote holds.

A full-credit answer: The zygote holds 5 from the abnormal gamete and 4 from the normal one: 9 chromosomes, a trisomy, with three copies of one chromosome.

Check the box for each point your answer earns

Common slip: Calling it a monosomy. An extra chromosome in a gamete gives three copies in the zygote.

Free-response score: 0 of 5
Free response 2 · Scientific Investigation · 4 points
Observation: in a species of sunflower, cells from plants grown in salty soil show fewer chiasmata in prophase I than cells from plants grown in ordinary soil.

(a) Construct a testable question about this observation that names what would be changed and what would be measured. (1 point)

A full-credit answer: Does the amount of salt in the soil change the mean number of chiasmata per cell in prophase I?
The amount of salt in the soil is changed and the number of chiasmata per cell is measured.

Check the box for each point your answer earns

Common slip: Asking why salty soil matters. A “why” question names nothing to change or measure.

(b) Identify the independent variable and the dependent variable in your question. (1 point)

A full-credit answer: The independent variable is the amount of salt in the soil; the dependent variable is the mean number of chiasmata per cell.

Check the box for each point your answer earns

Common slip: Swapping the two. What the experimenter changes is independent; what is measured is dependent.

(c) State the null hypothesis for the experiment. (1 point)

A full-credit answer: The amount of salt in the soil makes no difference to the mean number of chiasmata per cell; any difference between the groups is due to chance.

Check the box for each point your answer earns

Common slip: Stating that salty soil lowers the number of chiasmata. That is the alternative hypothesis, the prediction, not the null.

(d) Predict what fewer chiasmata per cell would mean for the fraction of recombinant gametes the salty-soil plants make, and explain why. (1 point)

A full-credit answer: Fewer chiasmata mean fewer crossovers, so fewer chromatids carry a combination of alleles neither homolog had, and a smaller fraction of the gametes are recombinant.

Check the box for each point your answer earns

Common slip: Saying the alleles themselves change. Crossing over recombines existing alleles; the number of alleles is unchanged.

Free-response score: 0 of 4
Multiple choice checked: 0 of 10 correct.