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Practice questions · Topic 5.2

Unit 5 · Practice for the Topic 5.2 end-of-topic test

You’ve gone through everything in this topic. The summary video below recaps it all, so you’re ready for the questions.

Watch first: Meiosis and genetic diversity, summed up

Video coming soon

Pairs that line up on their own and the two to the power of the pairs; non-sister chromatids trading pieces; any egg with any sperm; when a pair fails to separate, and how the counts say which division failed.

These are practice questions in the shape of the topic test. Work through them before you take the test; every question tells you what it wanted.
Answer every question. For each multiple-choice question, pick one option and press Check; the feedback tells you what a wrong choice assumed. For the free-response questions, write your answer in full sentences and show any calculation. The first free-response question walks you through one nondisjunction one part at a time, and you can open a hint for each part; the second is at the level of the test. When you finish a question, open the scoring guide and mark your own work against it. In every drawing, a chromosome from the mother is teal and one from the father is dark.
Question 1

A gamete from a dragonfly carries one chromosome of every pair.

Which statement describes where the chromosomes in that gamete came from?

Question 2

A slug has 3 pairs of chromosomes.

How many kinds of gamete can one slug make by independent orientation alone?

Question 3

In prophase I in a bee, two chromatids break at the same point and exchange pieces.

Which two chromatids are they?

Question 4

A rat’s homologous pair carries R and S on one homolog and r and s on the other. After one crossover between the two positions, the four chromatids are RS, Rs, rS and rs.

Which two are the parental combinations?

Question 5

In a species of crab, each parent makes 16 kinds of gamete by independent orientation.

How many kinds of zygote can two crabs make, counting independent orientation and random fertilization only?

Question 6

One chromatid in a guinea pig’s egg carries the mother’s allele of one gene and the father’s allele of the next gene along the same chromosome.

Which source of variation made that chromatid?

Question 7

A plant’s body cells hold 16 chromosomes. In one cell, one homologous pair undergoes nondisjunction in meiosis I; meiosis II runs normally.

What are the chromosome counts of the four cells produced?

Question 8

A fly’s body cells hold 8 chromosomes. The four cells from one meiosis hold 5, 3, 4 and 4.

Which division did the failure happen in?

Question 9

A sheep’s body cells hold 54 chromosomes. A sheep egg with 28 chromosomes is fertilized by a normal sperm with 27.

What does the zygote hold?

How to tackle the free-response questions. Read the verb first: describe asks what you see or know; explain asks why or how, so name the mechanism; predict asks what will happen and why; justify asks for the evidence that supports a claim. Each point is earned by one idea, stated in a sentence that names the thing and the mechanism. Extra words earn nothing; a wrong extra can lose the point. If there is a figure or table, use what it shows. When you finish, check the box for each point your answer earns and compare your sentences with the full-credit answer.
Free response 1 · Conceptual Analysis · 5 points
A plant’s body cells each hold 10 chromosomes. One cell in its anther goes through meiosis.

(a) Calculate the number of chromosomes in each of the four cells when meiosis runs normally. (1 point)

Hint: How many pairs does a cell with 10 chromosomes have, and how many of each pair does a gamete get?

Write down the values in the question:

2n=10

Write down the equation:

chromosomes per gamete=n=2n2

Substitute the values into the equation:

chromosomes per gamete=102=5

A full-credit answer: 5 chromosomes in each cell.

(b) Predict the four counts if one homologous pair undergoes nondisjunction in meiosis I and meiosis II runs normally. (1 point)

Hint: In meiosis I both members of one pair go to one cell; what does meiosis II then do to each of the two cells?

A full-credit answer: 6, 6, 4 and 4: one cell from meiosis I holds 6 and the other 4, and meiosis II gives two cells of each.

Check the box for each point your answer earns

Common slip: Writing 6, 4, 5, 5. That is the pattern of a failure in meiosis II.

(c) Predict the four counts if instead meiosis I is normal and, in one of the two cells, the sister chromatids of one chromosome undergo nondisjunction in meiosis II. (1 point)

Hint: Only one of the two cells from meiosis I fails; what does the other cell give?

A full-credit answer: 6, 4, 5 and 5: the cell that failed gives one cell of 6 and one of 4, and the other cell gives two normal cells of 5.

Check the box for each point your answer earns

Common slip: Writing 6, 6, 4, 4. Only one cell failed, so two of the four are normal.

(d) A set of four cells from a second cell of this plant holds 6, 6, 4 and 4. Identify the division in which the failure happened, and justify it from the counts. (1 point)

Hint: Compare this set with the two patterns you predicted in (b) and (c).

A full-credit answer: Meiosis I: no cell holds the normal count of 5, so the pair failed to part in meiosis I and both cells from meiosis I carried the error into meiosis II, which copied each count into two cells.

Check the box for each point your answer earns

Common slip: Choosing meiosis II because a cell is over and a cell is under. Both patterns have that; the cells with the normal count place the failure.

(e) Predict the chromosome number of the zygote made when the 6-chromosome gamete fuses with a normal gamete, and identify it as a trisomy or a monosomy. (1 point)

Hint: Add the abnormal gamete’s count to a normal gamete’s count, then ask how many copies of the extra chromosome the zygote holds.

A full-credit answer: 11 chromosomes: 6 from the abnormal gamete and 5 from the normal one, so three copies of one chromosome, a trisomy.

Check the box for each point your answer earns

Common slip: Calling it a monosomy. An extra chromosome in a gamete gives three copies in the zygote.

Free-response score: 0 of 5
Free response 2 · Scientific Investigation · 4 points
Observation: in a species of wheat, cells from plants grown in dry soil show fewer chiasmata in prophase I than cells from plants grown in well-watered soil.

(a) Write a testable question about this observation that names what would be changed and what would be measured. (1 point)

A full-credit answer: Does the amount of water given to the plants change the mean number of chiasmata per cell in prophase I? The amount of water is changed and the number of chiasmata per cell is measured.

Check the box for each point your answer earns

Common slip: Asking why dry soil matters. A “why” question names nothing to change or measure.

(b) Identify the independent variable and the dependent variable in your question. (1 point)

A full-credit answer: The independent variable is the amount of water given to the plants; the dependent variable is the mean number of chiasmata per cell.

Check the box for each point your answer earns

Common slip: Swapping the two. What the experimenter changes is independent; what is measured is dependent.

(c) State the null hypothesis for the experiment. (1 point)

A full-credit answer: The amount of water given to the plants makes no difference to the mean number of chiasmata per cell; any difference between the groups is due to chance.

Check the box for each point your answer earns

Common slip: Stating that dry soil lowers the number of chiasmata. That is the alternative hypothesis, the prediction, not the null.

(d) Predict what fewer chiasmata per cell would mean for the fraction of recombinant gametes the dry-soil plants make, and explain why. (1 point)

A full-credit answer: Fewer chiasmata mean fewer crossovers, so fewer chromatids carry a combination of alleles neither homolog had, and a smaller fraction of the gametes are recombinant.

Check the box for each point your answer earns

Common slip: Saying the alleles themselves change. Crossing over recombines existing alleles; the number of alleles is unchanged.

Free-response score: 0 of 4
Multiple choice checked: 0 of 9 correct.