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End-of-topic test: Continuing Evolution

Unit 7 · Topic 7.8 end-of-topic test

Suggested time: about 44 minutes. Answer everything, then press Submit the test to see the feedback and scoring guides.

Answer every question. For each multiple-choice question, pick one option and press Check; the feedback gives the reasoning. For the free-response questions, write one short sentence for each step of your reasoning, each on its own line, and make every link clear (so, because, therefore). That is what the exam’s ‘paragraph form’ means for you: linked sentences, not bullet points. Then open the scoring guide and mark your own work against it. Every count and every table in this test is imagined for the question.
Question 1
A table with three columns, measurement, the 1932 sample and the 2024 sample, and three rows: mean bill depth, 8.4 mm and 8.5 mm; frequency of allele J, 0.39 and 0.62; frequency of allele Z, 0.74 and 0.55Measurement1932 sample2024 samplemean bill depth8.4 mm8.5 mmfrequency of allele J0.390.62frequency of allele Z0.740.55100 adult songbirds from one valley in each year; the numbers are imagined
Two samples of one songbird population, 92 years apart: mean bill depth and the frequency of one allele at each of two genes; the numbers are imagined.

Biologists compare 100 adult songbirds collected in one valley in 1932 with 100 collected there in 2024. The table gives the mean bill depth and the frequency of one allele at each of two genes in each sample.

Which conclusion do the data support?

Question 2

A wildlife park breeds pelicans and keeps almost every chick alive to adulthood. A keeper says: “These pelicans have stopped evolving, because almost every chick survives.”

Is the keeper correct?

Question 3
A table with five columns, collection year, DNA copies read, and the percentage of copies with base G at position 114, with base T at position 308 and with base C at position 517, and three rows: 1980, 40, 0, 20, 85; 2000, 40, 15, 35, 70; 2020, 40, 30, 50, 60YearDNA copies readG at position 114T at position 308C at position 5171980400%20%85%20004015%35%70%20204030%50%60%one stretch of DNA read from 20 preserved beetles of one island population in each year; the percentages are imagined
One stretch of DNA read from 20 preserved beetles in each of three years: the share of the 40 DNA copies carrying a particular base at three positions; the percentages are imagined.

Biologists group the evidence that evolution continues today into four kinds. Researchers read one stretch of DNA from 20 preserved beetles of one island population in each of three years, as the table shows.

Which kind of evidence is this case?

Question 4

Which of the following observations is the evolution of resistance?

Question 5
A table with three columns, when, all cells and resistant cells, and three rows: before the antibiotic, 100,000,000 and 100; after course 1 and regrowth, 5,000,000 and 4,900,000; after course 2 and regrowth, 80,000,000 and 79,000,000WhenAll cells (per mL)Resistant cells (per mL)before the antibiotic100,000,000100after course 1 and regrowth5,000,0004,900,000after course 2 and regrowth80,000,00079,000,000a bacterium in a flask given two courses of one antibiotic, each followed by regrowth in fresh broth; the counts are imagined
A bacterium in a flask through two courses of one antibiotic, each followed by regrowth: all cells and resistant cells per mL; the counts are imagined.

Researchers grow a bacterium in a flask and give it two courses of one antibiotic. After each course they move the survivors to fresh broth and let them regrow. The table gives the counts of all cells and of resistant cells.

Which statement explains the change in the counts?

Question 6
A line graph with generation 0 to 10 on the x-axis and the share of the cells that are resistant, 0 to 1, on the y-axis, gridlines every 0.1; eleven dots joined by a line that starts low at the left, climbs slowly, then faster, then more slowly, ending high at the right; no values are printed00.20.40.60.81012345678910generationshare of the cells that are resistantgridlines every 0.1
The share of resistant cells in one flask over ten generations with a low dose of an antibiotic; no values are printed.

The graph shows the share of resistant cells in one flask of bacteria over ten generations with a low dose of an antibiotic.

Between which two generations did the share rise the most?

Question 7
A table with four columns, pathogen, number in one infected person, time for one generation and copying errors per copy of its genes, and four rows: a throat virus, ten billion, six hours, about one; a gut bacterium, one hundred million, one day, about 0.001; a skin fungus, ten thousand, one week, about 0.001; a blood parasite, one million, two days, about 0.01PathogenNumber in one personOne generationCopying errors per copya throat virus10,000,000,0006 hoursabout 1a gut bacterium100,000,0001 dayabout 0.001a skin fungus10,0001 weekabout 0.001a blood parasite1,000,0002 daysabout 0.01four pathogens compared; the numbers are imagined
Four pathogens compared: number in one infected person, time for one generation, copying errors per copy of the genes; the numbers are imagined.

The table compares four pathogens: how many are in one infected person, how long one generation takes, and how many copying errors each copy of its genes carries.

Which pathogen would most quickly produce a variant that escapes a drug?

Question 8
A table with five columns, disease, where it occurs, cases a year twenty years ago, cases a year now, and whether the usual drug still cures it, and four rows: the delta fever, one river delta, 3,000, 3,100, yes; the highland cough, one mountain region, 900, 950, no; the island rash, 1 island to 2021 and 4 islands from 2021, 400, 6,000, yes; the port fever, one port city, 12,000, 11,500, yesDiseaseWhere it occursCases, 20 years agoCases, nowDrug still cures itthe delta feverone river delta3,0003,100yesthe highland coughone mountain region900950nothe island rash1 island to 2021; 4 islands from 20214006,000yesthe port feverone port city12,00011,500yesfour diseases of people in one country; the numbers are imagined
Four diseases of people in one country: where each occurs, its cases a year twenty years ago and now, and whether the usual drug still cures it; the numbers are imagined.

Health officers list four diseases of people in one country, as the table shows.

Which disease is an emergent disease?

Question 9

A stomach virus spreads through two towns in one winter. In the first town most people had the same virus the winter before, so their blood carries antibodies that bind that virus’s surface protein. In the second town few people had it. In both towns a variant with a changed surface protein appears.

In which town does the variant become the common form sooner, and why?

Question 10

The greenkeepers of a golf course want resistance to a new fungicide to rise as slowly as possible in the fungus that attacks their turf.

Which policy would do that?

Question 11
A line graph with year 0 to 6 on the x-axis and the share of the caterpillars that are resistant, 0 to 1, on the y-axis, gridlines every 0.1; a legend names two lines, farm 1 and farm 2, each drawn through dots; one line climbs steeply to high values, the other climbs slowly and stays low00.20.40.60.810123456yearshare of the caterpillars that are resistantgridlines every 0.1farm 1farm 2
The share of resistant caterpillars on two cotton farms over six years; one farm sprays every week, the other every fourth week; no values are printed.

Two cotton farms spray the same insecticide against a caterpillar that eats cotton bolls. One farm sprays every week; the other sprays every fourth week. The graph shows the share of each farm’s caterpillars that survive the insecticide, year by year.

Which farm sprays every week, and what in the graph shows it?

Question 12

A student wants to know what share of the leafhoppers on a rice farm carry an allele for surviving a pesticide. The day after the farm sprays, she collects 50 leafhoppers from the sprayed field and finds that 47 carry the allele. She reports that 94% of the farm’s leafhoppers carry the allele.

What is the flaw in her study?

Question 13

A student estimated the share of a valley’s leafhoppers that carry an allele for surviving a pesticide. She read the allele in 40 leafhoppers that had hatched from the eggs laid on one rice plant: 30 carried it.

Which study would give a better estimate of the share in the valley’s leafhopper population?

Question 14

A biologist counts the cells of a bacterium in a jar of rainwater each day for four days. Each day’s count is ten times the day before’s, from 300 cells per mL on day 0 to 3,000,000 cells per mL on day 4. She plots the counts on a log scale.

What does her graph look like?

Question 15
A graph with time in days, 0 to 4, on the x-axis and a y-axis marked 10,000, 100,000, 1,000,000 and 10,000,000 at equal spacing, labeled log scale, with three dashed minor gridlines between each pair of marks; five dots joined by segments climb from day 0 to day 410,000100,0001,000,00010,000,00001234time (days)count (cells per mL, log scale)minor gridlines at 2, 3 and 5 times each mark
A bacterium in a vat of fermenting cabbage, counted each day and plotted on a log scale; no values are printed.

A technician counts the cells of a bacterium in a vat of fermenting cabbage each day. The graph plots the counts on a log scale; its minor gridlines sit at 2, 3 and 5 times each mark.

What is the count on day 3?

Question 16
A graph with time in days, 0 to 3, on the x-axis and a y-axis marked 10, 100, 1,000, 10,000 and 100,000 at equal spacing, labeled log scale, with three dashed minor gridlines between each pair of marks; four dots joined by segments; the line climbs to day 2 and then falls to day 3101001,00010,000100,0000123time (days)count (cells per mL, log scale)minor gridlines at 2, 3 and 5 times each mark
A student’s plot of four daily bacterial counts on a log scale; no values are printed.

A student counts the cells of a bacterium in a bowl of soup left out at room temperature, once a day: 70, 500, 4,000 and 25,000 cells per mL on days 0 to 3. She plots the four counts on a log scale, as the graph shows.

Which day’s point has the student placed at the wrong height?

How to tackle the free-response questions. Read the verb first: describe asks what you see or know; explain asks why or how, so name the mechanism; predict asks what will happen and why; justify asks for the evidence that supports a claim. Each point is earned by one idea, stated in a sentence that names the thing and the mechanism. Extra words earn nothing; a wrong extra can lose the point. If there is a figure or table, use what it shows. When you finish, check the box for each point your answer earns and compare your sentences with the full-credit answer.
Free response 1 · Analyze Data · 4 points
Researchers grow a bacterium isolated from seawater in a flask of broth. At 0 hours they count all the cells, and the cells that survive a full dose of an antibiotic (the resistant cells). Then they add a low dose of the antibiotic to the flask, and repeat both counts every four hours. The graph plots both counts on a log scale; its minor gridlines sit at 2, 3 and 5 times each mark.
A graph with time in hours, 0 to 16, on the x-axis and a y-axis marked 100 to 100,000,000 at equal spacing, labeled log scale, with three dashed minor gridlines between each pair of marks; a legend names two lines, all cells and resistant cells; the all-cells line starts high and climbs steadily; the resistant-cells line starts far lower and climbs more steeply, ending just below the all-cells line1001,00010,000100,0001,000,00010,000,000100,000,0000481216time (hours)count (cells per mL, log scale)all cellsresistant cells
All cells and resistant cells in one flask with a low dose of an antibiotic, counted every four hours and plotted on a log scale; no values are printed.

(a) Identify the count of all cells at 12 hours, and state the mark or gridline at which you read it. (1 point)

A full-credit answer: All cells at 12 hours: 3,000,000 cells per mL.
The point sits on the second minor gridline above the 1,000,000 mark, which is 3 times that mark: the 3,000,000 gridline.

Check the box for each point your answer earns

(b) At 16 hours the flask held 10,000,000 cells per mL, of which 8,000,000 were resistant. Calculate the percentage of the cells that were resistant at 16 hours. (1 point)

%

Write down the values in the question:

resistant cells at 16 hours = 8,000,000 per mL
all cells at 16 hours = 10,000,000 per mL

Write down the equation:

percentage resistant=resistant cellsall cells×100%

Substitute the values into the equation:

percentage resistant=8,000,00010,000,000×100%=80%

A full-credit answer: 8,000,000 of the 10,000,000 cells per mL were resistant.
8,000,000 ÷ 10,000,000 = 0.80, which is 80%.

(c) Describe how the share of the cells that were resistant changed between 8 and 12 hours. Use the graph. (1 point)

A full-credit answer: At 8 hours about 150,000 of the 1,000,000 cells per mL were resistant: about 15%.
At 12 hours about 2,000,000 of the 3,000,000 cells per mL were resistant: about 67%.
So the resistant share rose from about 15% to about 67%.

Check the box for each point your answer earns

Common slip: Giving the two resistant counts alone, without turning each into a share of all the cells.

(d) Determine whether the antibiotic created the allele for resistance or selected an allele already present. Support your answer with evidence from the graph. (1 point)

A full-credit answer: The antibiotic selected an allele already present.
At 0 hours, before the antibiotic was added, about 400 cells per mL already survived a full dose: the point sits between the 300 and 500 gridlines.
So the allele was in the flask before the drug.
The drug then killed cells without the allele, and the cells with it divided, so their share rose.

Check the box for each point your answer earns

Free-response score: 0 of 4
Free response 2 · Conceptual Analysis · 4 points
A virus long known in wild waterbirds changes, and the changed virus begins to infect people in fishing villages around a lake, where no one had had the disease before. In the first year 12 people fall ill; in the second year 900 do, and the disease is reported around two other lakes. People who recovered from the first year’s virus carry antibodies that bind its surface protein.

(a) Describe two features of the virus population that let it produce variants quickly. (1 point)

A full-credit answer: The virus population is huge: an infected person carries millions of copies.
Its generations are short: a copy is made within hours.
It mutates often: each copying of its genes brings copying errors.
Any two of these.

Check the box for each point your answer earns

(b) Explain how the antibodies of the people who recovered act as a selective pressure on the virus population, and why a variant with a changed surface protein spreads among them. (1 point)

A full-credit answer: Their antibodies bind the first year’s surface protein, and the body destroys the viruses they bind.
The antibodies fail to bind a variant whose surface protein has a changed shape, so that variant survives in them.
The variant copies itself and spreads; the first year’s form is destroyed.
So the antibodies sorted the variants: natural selection with immunity as the selective pressure.

Check the box for each point your answer earns

(c) Predict whether a variant with a changed surface protein has an advantage over the first year’s form among people who stayed healthy through the first year, and give the reason. (1 point)

A full-credit answer: No advantage.
Those people have no antibodies against either form.
So the first year’s form and the variant infect them alike, and neither is favored.

Check the box for each point your answer earns

(d) Evaluate whether the evidence supports classifying this disease as an emergent disease, and identify one further piece of evidence a health officer would need. (1 point)

A full-credit answer: The evidence supports it.
No one around the lake had had the disease before, so it appeared in a population for the first time.
Its cases rose from 12 to 900 in a year, and it was reported around two other lakes: rising fast and spreading into new places.
A health officer would still need the virus’s gene sequence from patients at the other lakes, to show that the same changed virus causes the cases there.

Check the box for each point your answer earns

Free-response score: 0 of 4
Feedback and scoring guides appear after you submit.
Multiple choice checked: 0 of 16 correct.