← Course menu

Practice questions · Topic 2.2

Unit 2 · Practice for the Topic 2.2 end-of-topic test

These are practice questions in the shape of the topic test. Work through them before you take the test; every question tells you what it wanted.
These practice questions have the shape of the Topic 2.2 test. Answer every question. For each multiple-choice question, pick one option and press Check; the feedback tells you what a wrong choice assumed. For the first free-response question, you work through one scenario in small steps, and each step offers a hint if you want one. For the second, write your answer in full sentences as you would in the test, then open the scoring guide and mark your own work against it. Formulas are given wherever a calculation needs them; use π = 3.14.
Question 1

A cube-shaped plant cell has sides 12 μm long. For a cube of side s, surface area = 6s² and volume = s³.

What are its surface area and its volume?

Question 2

A cell has a surface area of 220 μm² and a volume of 200 μm³.

What is its surface-area-to-volume ratio?

Question 3

A spherical cell grows without changing shape. Its radius increases from 1 μm to 4 μm.

Compared with the small cell, how have its surface area, volume and surface-area-to-volume ratio changed?

Question 4

Cells of a kind of bacterium normally divide whenever they reach 2 μm long. A drug stops them dividing but leaves them growing. At 8 μm long the cells take in oxygen too slowly for their needs and stop growing.

Why does the oxygen intake fall behind the cell's needs as it grows?

Question 5

A cube-shaped cell with sides 6 μm long can bring in, across its membrane, 120% of the oxygen its interior uses each minute. A cell of the same kind grows to a cube with sides 12 μm long. Oxygen intake is proportional to membrane area; oxygen use is proportional to volume.

What percentage of its oxygen need can the 12 μm cell's membrane supply?

Question 6

Each cell lining a kidney tubule carries thousands of finger-like projections of its plasma membrane, called microvilli, on the surface that faces the tubule fluid, from which the cell takes back useful substances. A cell with microvilli has about four times the membrane area of the same cell with a bare surface, and almost the same volume.

How do the microvilli aid exchange between the cell and the fluid around it?

Question 7

A hamster weighing 30 g and a dog weighing 30 kg spend a cold night in the same barn. Both keep their bodies at about 38 °C.

Which animal loses more heat per gram of body each hour, and why?

Question 8

A bat weighing 10 g and a cow weighing 600 kg are studied at rest. Per gram of body, the bat uses energy about 20 times as fast as the cow.

What does this show?

Question 9

A spherical yeast cell has a radius of 1 μm. For a sphere, surface area = 4πr² and volume = 4/3 πr³. Use π = 3.14.

What are its surface area, volume and surface-area-to-volume ratio?

Question 10

Two single-celled fungi take up nutrients across their surfaces. Cell J has a surface area of 80 μm² and a volume of 40 μm³. Cell K has a surface area of 120 μm² and a volume of 100 μm³.

Which cell exchanges nutrients with its surroundings more efficiently, for its size, and why?

How to tackle the free-response questions. Read the verb first: describe asks what you see or know; explain asks why or how, so name the mechanism; predict asks what will happen and why; justify asks for the evidence that supports a claim. Each point is earned by one idea, stated in a sentence that names the thing and the mechanism. Extra words earn nothing; a wrong extra can lose the point. If there is a figure or table, use what it shows. When you finish, check the box for each point your answer earns and compare your sentences with the full-credit answer.
Free response 1 · Analyze Model or Visual Representation · 5 points
The model shows two cube-shaped cells from an early embryo. Cell A has sides 5 μm long; its surface area is 150 μm², its volume 125 μm³ and its surface-area-to-volume ratio 1.2 per μm. Cell B has sides 10 μm long; its values are left blank. For a cube of side s, surface area = 6s² and volume = s³. Everything a cell takes in, and every waste it gets rid of, crosses its surface.

(a) Calculate the surface area and the volume of cell B, with units. (1 point)

Hint: Six faces for the surface; side × side × side for the volume.

A full-credit answer: Cell B has a surface area of 600 μm² and a volume of 1,000 μm³.

Write down the values in the question:

s = 10 μm

Write down the equations:

surface area = 6s²
volume = s³

Substitute in the values, and calculate:

surface area = 6 × 10²
surface area = 6 × 100
surface area = 600 μm²
volume = 10³
volume = 10 × 10 × 10
volume = 1,000 μm³

Check the box for each point your answer earns

Accept: 600 μm² and 1000 μm³. Do not award the point for 100 μm² (one face) or for volume given in μm².

Common slip: Giving 100 μm² for the surface. That is one face; a cube has six, and all six are surface.

(b) Calculate the surface-area-to-volume ratio of cell B, with its unit. (1 point)

Hint: Which quantity goes on top and which underneath? Then ask what unit is left when μm² is divided by μm³.

A full-credit answer: Cell B's surface-area-to-volume ratio is 600 ÷ 1,000 = 0.6 per μm.

Write down the values in the question:

surface area = 600 μm²
volume = 1,000 μm³

Write down the equation:

        surface area
SA/V = ──────────────
           volume

Substitute in the values, and calculate:

SA/V = 600 ÷ 1,000
SA/V = 0.6 per μm

Check the box for each point your answer earns

Accept: 0.6 μm⁻¹. Do not award the point for the inverted ratio, 1.67.

Common slip: Dividing the volume by the surface area to get 1.67. The ratio is surface over volume: it says how much surface serves each μm³.

(c) Describe how the surface area, the volume and the ratio changed when the side doubled from 5 μm to 10 μm, using the numbers in the model. (1 point)

Hint: Divide each of B's values by A's to find the factor; then compare the two factors.

A full-credit answer: When the side doubled, the surface area went from 150 to 600 μm², a factor of 4, while the volume went from 125 to 1,000 μm³, a factor of 8. The volume grew faster than the surface area, so the ratio halved, from 1.2 to 0.6 per μm.

Write down the values in the question:

cell A: surface area = 150 μm², volume = 125 μm³, SA/V = 1.2 per μm
cell B: surface area = 600 μm², volume = 1,000 μm³, SA/V = 0.6 per μm

Write down the equation:

         value for cell B
factor = ────────────────
         value for cell A

Substitute in the values, and calculate:

surface area factor = 600 ÷ 150
surface area factor = 4
volume factor = 1,000 ÷ 125
volume factor = 8
ratio factor = 0.6 ÷ 1.2
ratio factor = 0.5

Check the box for each point your answer earns

Accept: the factors 4 and 8 with the ratio described as falling or halving. Do not award the point for "both got bigger" with no factors.

Common slip: Saying both got bigger. The point needs the two factors, 4 and 8, or the ratio halving, to show that volume outran surface.

(d) Explain why a falling surface-area-to-volume ratio limits how large a cell can grow. (1 point)

Hint: What does each quantity in the ratio stand for in a living cell? Which one is the route in and out, and which one is the amount of cell that has to be supplied?

A full-credit answer: A cell takes in what it needs and gets rid of wastes only across its surface, while the amount it needs grows with its volume. As the cell grows, the volume outruns the surface, so less and less surface serves each μm³ of interior. Past a certain size the surface can no longer bring in enough, or get rid of enough, for the interior, and the cell cannot keep growing.

Check the box for each point your answer earns

Accept: "supply grows with surface, demand grows with volume, and volume grows faster".

Common slip: Saying 'bigger cells need more' without linking surface to supply and volume to demand. The point is that the two grow at different rates.

(e) Predict what the embryo's cells do as they grow toward the size of cell B, and justify your prediction using the ratio. (1 point)

Hint: Think about the two ways a cell can keep its surface able to serve its interior, and which one an embryo uses.

A full-credit answer: As the cells approach B's size they divide rather than growing without limit. A 10 μm cell has only 0.6 μm² of surface for each μm³, half what a 5 μm cell has; dividing it into smaller cells brings the ratio back up to 1.2 per μm, so each new cell's surface can again keep up with its interior.

Check the box for each point your answer earns

Accept: "they divide, restoring more surface per μm³". Do not award the point for "they grow bigger to get more surface".

Common slip: Predicting that the cells grow larger to gain surface. They do gain surface in total, but they gain volume faster; dividing is what restores surface per μm³.

Free-response score: 0 of 5
Free response 2 · Conceptual Analysis · 4 points
Two kinds of bacterium live in the same soil water and take up dissolved nutrients across their surfaces. Species R is rod-shaped and is modeled as a cylinder of radius 0.5 μm and length 2 μm. Species S is round and is modeled as a sphere of radius 0.75 μm. Formulas: cylinder, surface area = 2πrh + 2πr², volume = πr²h; sphere, surface area = 4πr², volume = 4/3 πr³. Use π = 3.14.

(a) Calculate the surface-area-to-volume ratio of each cell, showing the surface area and the volume you used, with units. (1 point)

A full-credit answer: Species R has a surface area of 7.85 μm² and a volume of 1.57 μm³, so its ratio is 5.0 per μm. Species S has a surface area of 7.07 μm² and a volume of 1.77 μm³, so its ratio is 4.0 per μm.

Write down the values in the question:

R: r = 0.5 μm, h = 2 μm, π = 3.14
S: r = 0.75 μm, π = 3.14

Write down the equations:

cylinder: surface area = 2πrh + 2πr²
cylinder: volume = πr²h
sphere: surface area = 4πr²
                 4
sphere: volume = ─ πr³
                 3
        surface area
SA/V = ──────────────
           volume

Substitute in the values, and calculate:

R surface area = 2 × 3.14 × 0.5 × 2 + 2 × 3.14 × 0.5²
R surface area = 6.28 + 1.57
R surface area = 7.85 μm²
R volume = 3.14 × 0.5² × 2
R volume = 1.57 μm³
R SA/V = 7.85 ÷ 1.57
R SA/V = 5.0 per μm
S surface area = 4 × 3.14 × 0.75²
S surface area = 7.07 μm²
S volume = 4 ÷ 3 × 3.14 × 0.75³
S volume = 1.77 μm³
S SA/V = 7.07 ÷ 1.77
S SA/V = 4.0 per μm

Check the box for each point your answer earns

Accept: ratios with the working shown even if an intermediate value is rounded differently. Do not award the point for inverted ratios or for one cell only.

Common slip: Forgetting the two end circles of the cylinder (2πr²), or dividing volume by surface. Surface over volume, for both cells, with every face counted.

(b) Identify which species takes up nutrients more efficiently for its size, and explain why. (1 point)

A full-credit answer: Species R takes up nutrients more efficiently for its size. Its ratio is 5.0 per μm against S's 4.0, so each μm³ of R has more membrane serving it. Nutrients enter only across the membrane, and the need for them grows with the volume, so more surface per unit of volume means faster supply.

Check the box for each point your answer earns

Accept: "R: more surface per unit of volume, so faster exchange for the same interior".

Common slip: Choosing S because its volume is larger. More volume is more interior to supply; what matters for efficiency is surface for each unit of volume.

(c) Predict what happens to the ratio of species S, and to how well its surface can supply its interior, if a cell doubles its radius to 1.5 μm before dividing. (1 point)

A full-credit answer: Doubling the radius multiplies the surface by 4, to 28.3 μm², and the volume by 8, to 14.1 μm³, so the ratio halves to 2.0 per μm. The surface supplies the interior less well: exchange cannot keep pace with the larger volume.

Write down the values in the question:

r = 1.5 μm
π = 3.14

Write down the equations:

surface area = 4πr²
         4
volume = ─ πr³
         3
        surface area
SA/V = ──────────────
           volume

Substitute in the values, and calculate:

surface area = 4 × 3.14 × 1.5²
surface area = 28.3 μm²
volume = 4 ÷ 3 × 3.14 × 1.5³
volume = 14.1 μm³
SA/V = 28.3 ÷ 14.1
SA/V = 2.0 per μm

Check the box for each point your answer earns

Accept: "the ratio falls (halves) and exchange becomes less efficient" with the direction of both changes stated.

Common slip: Saying the ratio rises because the cell has more surface. It has more surface in total but far more volume, so less surface for each μm³.

(d) The cells lining a mammal's gut have surfaces folded into thousands of tiny projections. Justify the claim that these folds use the same principle as the shapes of the two bacteria. (1 point)

A full-credit answer: The folds, the microvilli, add membrane surface to the cell while adding almost no volume, so they raise its surface-area-to-volume ratio, the same quantity that makes the rod-shaped R more efficient than the round S. In both cases more surface for each unit of volume means the membrane can take up nutrients faster for the interior it serves.

Check the box for each point your answer earns

Accept: "folds add surface without adding volume; higher ratio; faster exchange", with the link to the bacteria's shapes stated. Do not award the point for "folds make the cell bigger".

Common slip: Saying the folds make the cell larger. The volume barely changes; the folds add surface, and surface per unit of volume is what speeds exchange.

Free-response score: 0 of 4
Multiple choice checked: 0 of 10 correct.